Common local reactions to vaccines include pain, swelling, and redness at the injection site.
Systemic reactions, including fever, irritability, drowsiness, and rash, may also occur.
Mild to Moderate Problems Mild rash, lasting 2-4 days.
Swelling and tenderness of lymph nodes, lasting 2-4 weeks after the blister has healed.
Fever of over 100°F (about 70% of children, 17% of adults) or over 102°F (about 15%-20% of children, under 2% of adults).
Secondary blister elsewhere on the body (about 1 per 1,900).
Moderate to Severe Problems Serious eye infection, or loss of vision, due to spread of vaccine virus to the eye.
Rash on entire body (as many as 1 per 4,000).
Severe rash on people with eczema (as many as 1 per 26,000).
Encephalitis (severe brain reaction), which can lead to permanent brain damage (as many as 1 per 83,000).
Severe infection beginning at the vaccination site (as many as 1 per 667,000, mostly in people with weakened immune systems).
Death (1-2 per million, mostly in people with weakened immune systems).
For every million people vaccinated, between 14 and 52 could have a life-threatening reaction to vaccines.
Systemic reactions, including fever, irritability, drowsiness, and rash, may also occur.
Mild to Moderate Problems Mild rash, lasting 2-4 days.
Swelling and tenderness of lymph nodes, lasting 2-4 weeks after the blister has healed.
Fever of over 100°F (about 70% of children, 17% of adults) or over 102°F (about 15%-20% of children, under 2% of adults).
Secondary blister elsewhere on the body (about 1 per 1,900).
Moderate to Severe Problems Serious eye infection, or loss of vision, due to spread of vaccine virus to the eye.
Rash on entire body (as many as 1 per 4,000).
Severe rash on people with eczema (as many as 1 per 26,000).
Encephalitis (severe brain reaction), which can lead to permanent brain damage (as many as 1 per 83,000).
Severe infection beginning at the vaccination site (as many as 1 per 667,000, mostly in people with weakened immune systems).
Death (1-2 per million, mostly in people with weakened immune systems).
For every million people vaccinated, between 14 and 52 could have a life-threatening reaction to vaccines.
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